2314 Aquired keratoglobus and Ehlers-Danhlos syndrome: A clinical and histopathological study

PREVALENCE OF KERATOCONUS I92P.Y. Santiago, 1~. Assouline, 2F. Ducoussnu, 2s. Bzwin, 2J.C. Ballion, 1~. Mezraoui, IY. Pouliquen llhpnrtment of Ophtl~almology. HBtcl-Dieu de Paris; 2HBpital d’lnstruction dcs ArmCcs II. Piquf, Bordeaux-Am&x Purpose: To determine the prevalence of keratoconus (KC) in a “normal” t~opolation and to pmvidc statislical rcfcrcncc wlocs Ihr cornwl topography nun~c~ic:~I dcsuiptwb Mctbuds: All 670 subjec&, age 18 to 22 y.. front a single class were examined during the military duty incorporation process in the French Armed Forces. Objective and mwifest refraction wcrc determined with ao autorefractometer and comeal topography was assessed using a TMS-I system Data were analyzed using 13 descriptors of comeal powers dis(ributioo from the new TMS-I statistical sofiwnrc and an artilicial intelligence based keratoconus prediction index (KC%, version IS). Results: 22 eyes (from 21 subjects) in 1340 had power distribution and KC% index compalible whh the diagnosis of kcraloconus. Qualitative analysis of color coded maps authentified “true” KC in 9 eyes (including a bilateral case), all with KC% greater than 30%. However further topographical evaluation of these cases revealed 3 pseudokeratoconus.